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Conclusions: Prospective, controlled, cost-effectiveness studies of complementary therapies have been carried out in the UK only for spinal manipulation (four studies) and acupuncture (two studies). The limited data available indicate that the use of these therapies usually represents an additional cost to conventional treatment. Peter H. Canter, Joanna Thompson Coon, and Edzard Ernst, Evidence Based Complementary and Alternative Medicine (December 2006)