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Conclusion: Individualised herbal medicine, as practised in European medical herbalism, *Chinese herbal medicine* and Ayurvedic herbal medicine, has a very sparse evidence base and there is no convincing evidence that it is effective in any indication. Because of the high potential for adverse events and negative herb-herb and herb-drug interactions, this lack of evidence for effectiveness means that its use cannot be recommended. R Guo , P H Canter , E Ernst, Postgraduate Medical Journal 2007;83:633-637 (October 2007)